Current Research Projects

AIM-ASD: Language intervention for children with ASD

AIM-ASD: Adaptive Interventions for Minimally Verbal Children with ASD

Nickname: AIM-ASD
Date: January 2013 - January 2018
Participants: Children 5-8 years old with a diagnosis of autism or PDD-NOS and low language ability
Funding: NICHDNIDCD
Clinic Trials: NCT01751698
In the news: personalized approach enhances communicationtablets may help children with ASD

Summary: This study uses two interventions (JASP-EMT and CORE- DTT) that have shown promise for optimizing social communication and spontaneously spoken words in minimally verbal children with ASD.  The study utilizes a novel design to evaluate and construct an optimal intervention path for each individual child.

Status: Open for enrollment. If you are interested in participating in this study, please contact us at: 310-206-1268. Get more information at the AIM-ASD website.

      AIM-ASD

Children showing early signs of ASD

Baby JASPER: Joint Engagement in Infants at Risk for ASD

Nickname: Baby JASPER
Date: January 2013 - January 2018 (estimated)
Participants: Infants 12-21 months old
Funding: NICHD ACE center
Clinic Trials: NCT01874327

Summary: The study evaluates a novel intervention that aims to improve joint attention and joint engagement skills with infants 12 to 21 months old who are at risk of developing an Autism Spectrum Disorder. Intervention takes place in a classroom setting and in the home.

Status: Open for enrollment. If you are interested in participating in this study, please contact us at: 310-206-1268.

Behavioral-medicinal language intervention

Augmenting Language Interventions for ASD: A Translational Approach

Nickname: CCNIA-Med, Project 3
Date: August 2012 - August 2017
Participants: Children 6 to 11 years with autism, asperger’s, or PDD-NOS
Funding: NICHD ACE center

Summary: This innovative project tests the hypothesized benefits of aripiprazole (ARI) versus placebo on short-term social communication and language outcomes in children with ASD. The main outcome of this treatment is language acquisition. Findings from this study are hoped to inform an empirically based approach to intervention choices for school age children with ASD and low language ability. Sessions take place at UCLA and in the home.

Status: Open for enrollment. If you are interested in participating in this study, please contact us at: 310-794-2215.

Language Intervention for children with DS

Early Communication Intervention for Children with Down Syndrome

Date: June 2014 - December 2018
Participants: Children age 30-54 months with Down syndrome
Funding: NIH
Clinic Trials: NCT02158390

Summary: This intervention seeks to improve language and social communication skills in children with Down syndrome who have limited language. This study examines the effectiveness of an early intervention program that uses the iPad as a mode of communication. The child receives treatment from both the interventionist and the caregiver.

Status: Open for enrollment. If you are interested in participating in this study, please contact us at: 310-206-1268.

Early intervention for spoken communication

Multisite RCT of Early Intervention for Spoken Communication in Autism

Nickname: ICAN
Date: July 2009 - February 2014
Participants: 33 Months to 54 Months
Funding: NIH
Clinic Trials: NCT02158390

Summary: The goal of this project is to compare the efficacy of two interventions for improving spoken language and reducing symptoms of autism: Discrete trial training (DTT) and Interpersonal developmental approach (IDA). DTT is an applied behavior analysis approach emphasizing highly structured teaching of school readiness skills. IDA is a visually supported, child-focused, flexible engagement, social communicative engagement approach on joint attention, symbolic play, and the use of conventional symbols within socially valid communicative contexts.

Status: No longer recruiting

AIR-B II: JASPER for preschoolers with autism

AIR-B II: Deployment Focused Model of JASPER for Preschoolers with Autism

Nickname: AIR-B II, Preschool Deployment
Date: December 2011 - November 2014
Participants: Preschool aged children with ASD
Funding: Autism Speaks

Summary: The goal of this study is to work in collaboration with the Los Angeles Unified School District (LAUSD) to bring interventions that can be implemented by the LAUSD staff into preschools across the district. We are working with the teachers and staff to improve social communication in children with ASD by targeting play and language skills. Classrooms receive either JASPER powerpoint or JASPER live coaching. The intervention focuses on supporting teaching professionals in implementing JASPER strategies to improve the social and communication outcomes of the children they work with.

Status: No longer recruiting

AIR-B II: Remaking Recess

AIR-B II: Remaking Recess

Nickname: AIR-B II, Remaking Recess
Date: November 2012 - June 2014
Participants: Children 4 years and older
Funding: HRSA
Clinic Trials: NCT01724047

Summary: The primary goal of this study is to identify intervention strategies that can improve outcomes for children with ASD and can be implemented  by school personnel in under served elementary schools. The intervention takes place during recess or lunch where children with autism may have the most difficulty interacting with peers.

Status: No longer recruiting. Get more information about this project at the Remaking Recess website and the AIR-B Network website.

aRemaking Recess       AIR-B network

AIR-B II: Tools for Teachers

AIR-B II: Schedules, Tools, and Activities for Transitions in the Daily Routine

Nickname: AIR-B II, Preschool deployment, STAT
Date: November 2012 - June 2014
Participants: Children 4 years and older
Funding: HRSA
Clinic Trials: NCT01724047

Summary: The primary goal of this study is to identify intervention strategies that can improve outcomes for children with ASD, and can be implemented  by school personnel in under served elementary schools. This study takes place at the child's school and tracks the behavioral progress of children whose teachers receive training. Study staff visit the school on a weekly basis to give teachers evidence-based strategies for teaching children with autism.

Status: No longer recruiting. Get more information about this project at the AIR-B Network website.

AIR-B network

AIR-B III: Building Better Bridges, Minding the Gap

AIR-B III: Building Better Bridges, Minding the Gap

Nickname: AIR-B III, Building Better Bridges, Minding the Gap
Date: September 2015 - Present
Participants: 
Funding: HRSA
Clinic Trials:

Summary: Our focus is on families with children with autism living in under-resourced contexts who must navigate the complex world of evaluations, diagnoses, interventions and resources. Over the next 5 years, our AIR-B team will conduct research, develop tools, and disseminate information into the community. For both studies, we will work with local community partners, regional centers, school districts, and parents of children with ASD. Our AIR-B research partner, Healthy African American Families (HAAF), a community based non-profit health agency led by Loretta Jones, CEO will help us design interventions that are culturally tailored and effective for the participants in each of our communities. We gained important feedback on our proposed studies and will continue to obtain community input through focus groups and interviews. By collaborating with diverse communities we are learning how to bring evidence supported interventions to families and children with ASD and particularly to those with the most unmet need.

Status: Currently Recruiting. Get more information about this project at the AIR-B Network website.

AIR-B network

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